Extravasation Of Phenergan
Common symptoms include inflammation, tightness or coolness of the skin, and pain around the IV site Both an infiltration and extravasation involve an IV solution or medication being delivered into the tissue surrounding the vein instead of into the vein itself. Rarer causes: pregnancy, exacerbation of the extradural bleed. The incidence of extravasation injury depends on both the patient and the medication, with nonvesicant extravasations occurring in 0.1–6% of adult patients and up to 11% of pediatric patients. It may also be used for sedating people who are agitated or anxious. Irritants can result in pain at the IV site and along the vein and may or may not cause inflammation extravasation or compartment syndrome. Give the medication only through a large-bore vein (preferably via a central venous access site, but absolutely no hand or wrist veins). Learn vocabulary, terms, and more with flashcards, games, and other study tools. P roblem: Promethazine (Phenergan, Wyeth) is a commonly used injectable product that possesses antihistamine, sedative, anti-motion sickness, and anti-emetic effects.The drug is also a known vesicant that is highly caustic to the intima of blood vessels and surrounding tissue. If there is an extravasation of an irritant medication, you will notice some redness, swelling, itchiness and possible discomfort at the site of your intravenous (IV) catheter Phenergan injection can cause severe irritation and damage extravasation of phenergan to tissues regardless of the route of administration. Did you reach this page by following a link on the School of Pharmacy Web site? Irritation and damage can also result from perivascular extravasation, unintentional intra-arterial injection, and intraneuronal or perineuronal infiltration Extravasation of Irritants. It is available by mouth as a syrup, as a rectal suppository, or by injection into a muscle Common side effects include confusion and sleepiness.. While Phenergan’s labeling warned against intra-arterial injection and perivascular extravasation and advised that “[w]hen administering any irritant drug intravenously it is usually preferable to inject it through the tubing of an intravenous infusion set that is known to be function-. Administer the medication through large patent veins (i.e., preferably via a central venous access site, absolutely no hand or wrist veins). Accidental intra-arterial injection or perivascular extravasation during administration of promethazine HCl injection can lead to vascular and tissue damage. Their expert opined that plaintiff's symptoms were inconsistent with extravasation (leakage) of Phenergan, and that, in any event, there was no causal relationship between extravasation and the alleged injuries, reflex sympathetic dystrophy (RSD) and fibromyalgia Problem: Promethazine (Phenergan, Wyeth) is a commonly used injectable product that possesses antihistamine, sedative, anti-motion sickness, and anti-emetic effects. The patient did not complain of any pain or burning, but while flushing with another NS flush I noticed swelling above the IV site Promethazine (Phenergan) is an irritant that can result in profound tissue damage and possible amputation if not administered properly. Promethazine is a phenothiazine-deriva- Clinical Alert is published periodically by the Office of. AU - Cingle, Colleen M. Promethazine (Phenergan) is a drug commonly prescribed in emergency departments and urgent care clinics for treatment of a variety of conditions (Table 1). Extravasation may occur due to either the cannula piercing the vessel wall or from increased venous pressure that causes leakage around the original venepuncture site. Title: Microsoft Word - Extravasation Treatment Table Non-Chemo June 2016.docx Author: fostersj Created Date: 8/12/2016 1:10:46 PM. The effects include bronchoconstriction, vasodilation and spasmodic contractions of gastrointestinal smooth muscle III. There are several chemotherapeutic agents with vesicant properties, and…. Phenergan medicine relief, eg to people having been on auscultation, pleural space. Extravasation can also be recognized more quickly when promethazine is diluted than if the drug is given in a smaller volume. This article describes prevention and management of extravasation from a peripheral catheter UW Health Clinical Tool Terms. See id., at 73, 75–76. General recommendations for midline administration: A. Promethazine is an antihistamine. A common complication of IV therapy is IV infiltration, when fluid leaks out of the vein into surrounding soft tissue.